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KMID : 0362919850030010009
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1985 Volume.3 No. 1 p.9 ~ p.12
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Radiosensitivity and Dose-Survival Characteristics of Crypt Cells of Mouse Jejunum
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Huh Seung-Jae
Park Charn-Il
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Abstract
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To determine the radiosensitivity and dose-survival characteristics of jejunal crypt cells, experimental study was done using total 40 mice. Single irradiation of 1,000rad to 1,600rad was delivered to whole bodies of mice, using a cesium 137 animal irradiator. The number of regenerating crypts per jejunal circumference was counted, by using a jejunal crypt cell assay technique, and dose response curve was measured. The average number of jejunal crypt per circumference in control group was 140±10. Mean lethal dose(D0) of mouse jejunal crypt cell was 135rad.
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